https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Genome-wide analysis of long noncoding RNA stability https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21737 16 h). Analysis of lncRNA features revealed that intergenic and cis-antisense RNAs are more stable than those derived from introns, as are spliced lncRNAs compared to unspliced (single exon) transcripts. Subcellular localization of lncRNAs indicated widespread trafficking to different cellular locations, with nuclear-localized lncRNAs more likely to be unstable. Surprisingly, one of the least stable lncRNAs is the well-characterized paraspeckle RNA Neat1, suggesting Neat1 instability contributes to the dynamic nature of this subnuclear domain. We have created an online interactive resource (http://stability.matticklab.com) that allows easy navigation of lncRNA and mRNA stability profiles and provides a comprehensive annotation of ∼7200 mouse lncRNAs.]]> Wed 11 Apr 2018 11:06:11 AEST ]]> Different types of disease-causing noncoding variants revealed by genomic and gene expression analyses in families with X-linked intellectual disability https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49050 Wed 03 May 2023 15:40:01 AEST ]]> The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27851 Thu 17 Mar 2022 14:39:27 AEDT ]]> Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20754 Sat 24 Mar 2018 08:00:25 AEDT ]]> Whole Genome Sequencing Improves Outcomes of Genetic Testing in Patients With Hypertrophic Cardiomyopathy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42320 Mon 22 Aug 2022 09:49:26 AEST ]]>